Is vancomycin monitoring of real value in pediatric cancer patients?

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[Therapeutic monitoring of vancomycin in critical care pediatric patients].

INTRODUCTION Vancomycin is used in pediatric patients usually at 40 mg/kg/day four times daily. Recent data demonstrated the need of large doses to reach therapeutic concentrations in critical patients. OBJECTIVE Describe dosage regime of vancomycin in patients from a pediatric intensive care unit, register values of plasmatic concentrations and determine the regimes necessary to reach therap...

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How much vancomycin dose is enough for the MRSA infection in pediatric patients with various degrees of renal function?

Today, an increase in vancomycin dose has been proposed to ensure efficacy. However, the risk of nephrotoxicity will increase with the dose. This study was aimed at evaluating the dosage regimens of vancomycin in pediatric patients based on pharmacokinetics/pharmacodynamics (PK/PD) and to optimize dosage individualization. Population pharmacokinetics analysis was performed on 155 Chinese childr...

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How much vancomycin dose is enough for the MRSA infection in pediatric patients with various degrees of renal function?

Today, an increase in vancomycin dose has been proposed to ensure efficacy. However, the risk of nephrotoxicity will increase with the dose. This study was aimed at evaluating the dosage regimens of vancomycin in pediatric patients based on pharmacokinetics/pharmacodynamics (PK/PD) and to optimize dosage individualization. Population pharmacokinetics analysis was performed on 155 Chinese childr...

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monitoring of serum vancomycin concentrations in pediatric patients with normal renal function

vancomycin is a a glycopeptide antibiotic with bacetiocidal effects on gram positive bacteria by interfering with cell wall synthesis. the necessity for monitoring of serum vancomycin concentrations (svcs) has been recently noticed at many institutions because of concerns for its nephrotoxicity. we aimed to describe the svcs monitoring in pediatric patients, in an effort to determine subtherape...

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Vancomycin use in hospitalized pediatric patients.

OBJECTIVES To assess vancomycin utilization at children's hospitals, to determine risk factors for vancomycin use and length of therapy, and to facilitate adapting recommendations to optimize vancomycin prescribing practices in pediatric patients. METHODS Two surveys were conducted at Pediatric Prevention Network hospitals. The first (Survey I) evaluated vancomycin control programs. The secon...

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ژورنال

عنوان ژورنال: Medicine Science | International Medical Journal

سال: 2017

ISSN: 2147-0634

DOI: 10.5455/medscience.2017.07.8668